Plague was programmed by John Shramko for use in an introductory Microbiology class. You will use your mouse to spray colonies of creatures, each color coded for different genetic traits, onto a pre-made or custom designed field. Watch the dynamic interaction of growth, travel, birth, and death. Unleash clouds of infection which will spread or perish, depending on the conditions you choose.
Share this gameFacebook Twitter Google+ Reddit
Got some great memories playing Plague? Share them with us and other DOS game enthousiasts!
PaulineMay 05, 2018
I always loved playing around with this simulator!! I wish there were an updated modern version that ran better on windows! Even with Dosbox the game bogs down with too many units on the screen. I still love it, though. <3